Fueled by a sense of mission and the recognition that neither government nor the private sector alone can set society on an optimal course, foundations play a unique role in propelling change. Philanthropy’s power comes from its willingness to test new ideas, measure outcomes, and accept that failure can sometimes be the price of experimentation. Above all, it comes from the recognition that the health of communities, nations, and indeed the planet, are not predetermined, but can be altered by strategic thinkers who have the smarts and resources to make things better. Learn where some of the most impactful foundations are placing their bets to advance science and build a healthy future.